Angelina said: "She looks like Brad. It's funny because she's almost going to be the outcast in the family because she's blonde and blue-eyed."
The 32-year-old actress also revealed she feels "more" of a connection to her adopted children Maddox, six, Pax, three, and two-year-old Zahara, than she does to "privileged" 18-month-old Shiloh.
Angelina explained to Look magazine: "I felt so much more for Madd, Zahara and Pax because they were survivors.
"Shiloh seemed so privileged from the moment she was born.
"But I'm conscious that I have to make sure I don't ignore her needs, just because I think the others are more vulnerable."